| Reaction Details |
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 | Report a problem with these data |
| Target | Neurotensin receptor type 2 |
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| Ligand | BDBM50069092 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1466613 (CHEMBL3407206) |
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| Ki | 6339±n/a nM |
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| Citation |  Thomas, JB; Giddings, AM; Olepu, S; Wiethe, RW; Warner, KR; Sarret, P; Longpre, JM; Runyon, SP; Gilmour, BP The amide linker in nonpeptide neurotensin receptor ligands plays a key role in calcium signaling at the neurotensin receptor type 2. Bioorg Med Chem Lett25:2060-4 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neurotensin receptor type 2 |
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| Name: | Neurotensin receptor type 2 |
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| Synonyms: | High-affinity levocabastine-sensitive neurotensin receptor | NT-R-2 | NTR2_RAT | Neurotensin receptor 2 | Neurotensin receptor type 2 | Ntr2 | Ntsr2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46280.50 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1466615 |
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| Residue: | 416 |
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| Sequence: | METSSPWPPRPSPSAGLSLEARLGVDTRLWAKVLFTALYSLIFAFGTAGNALSVHVVLKA
RAGRPGRLRYHVLSLALSALLLLLVSMPMELYNFVWSHYPWVFGDLGCRGYYFVRELCAY
ATVLSVASLSAERCLAVCQPLRARRLLTPRRTRRLLSLVWVASLGLALPMAVIMGQKHEV
ESADGEPEPASRVCTVLVSRATLQVFIQVNVLVSFALPLALTAFLNGITVNHLMALYSQV
PSASAQVSSIPSRLELLSEEGLLGFITWRKTLSLGVQASLVRHKDASQIRSLQHSAQVLR
AIVAVYVICWLPYHARRLMYCYIPDDGWTNELYDFYHYFYMVTNTLFYVSSAVTPILYNA
VSSSFRKLFLESLGSLCGEQHSLVPLPQEAPESTTSTYSFRLWGSPRNPSLGEIQV
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| BDBM50069092 |
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| n/a |
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| Name | BDBM50069092 |
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| Synonyms: | CHEMBL3403508 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H24FN3O4 |
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| Mol. Mass. | 437.4635 |
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| SMILES | COc1ccccc1-c1cc(NC(=O)C2(CCCCC2)C(O)=O)nn1-c1ccc(F)cc1 |
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| Structure | 
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