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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neurotensin receptor type 2 | ||
| Ligand | BDBM50069091 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1466615 (CHEMBL3404057) | ||
| EC50 | 55±n/a nM | ||
| Citation |  Thomas, JB; Giddings, AM; Olepu, S; Wiethe, RW; Warner, KR; Sarret, P; Longpre, JM; Runyon, SP; Gilmour, BP The amide linker in nonpeptide neurotensin receptor ligands plays a key role in calcium signaling at the neurotensin receptor type 2. Bioorg Med Chem Lett25:2060-4 (2015) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neurotensin receptor type 2 | |||
| Name: | Neurotensin receptor type 2 | ||
| Synonyms: | High-affinity levocabastine-sensitive neurotensin receptor | NT-R-2 | NTR2_RAT | Neurotensin receptor 2 | Neurotensin receptor type 2 | Ntr2 | Ntsr2 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 46280.50 | ||
| Organism: | Rattus norvegicus | ||
| Description: | ChEMBL_1466615 | ||
| Residue: | 416 | ||
| Sequence: |
| ||
| BDBM50069091 | |||
| n/a | |||
| Name | BDBM50069091 | ||
| Synonyms: | CHEMBL3403507 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H26FN3O5 | ||
| Mol. Mass. | 467.4894 | ||
| SMILES | COc1cccc(OC)c1-c1cc(NC(=O)C2(CCCCC2)C(O)=O)nn1-c1ccc(F)cc1 |(2.94,7.42,;3.73,6.48,;5.25,6.75,;5.77,8.2,;7.28,8.47,;8.28,7.3,;7.76,5.85,;8.75,4.67,;9.97,4.89,;6.25,5.58,;5.62,4.17,;4.11,3.85,;3.97,2.33,;2.63,1.56,;2.63,.02,;3.7,-.59,;1.33,-.77,;1.33,.77,;,1.54,;-1.33,.77,;-1.33,-.77,;,-1.54,;1.3,-2.29,;.23,-2.91,;2.36,-2.91,;5.35,1.69,;6.38,2.84,;7.92,2.67,;8.91,3.84,;10.43,3.56,;10.94,2.11,;12.15,1.89,;9.94,.94,;8.43,1.22,)| | ||
| Structure | 
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