| Reaction Details |
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 | Report a problem with these data |
| Target | Hepatocyte growth factor activator |
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| Ligand | BDBM50069125 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1466696 (CHEMBL3404294) |
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| IC50 | >50000±n/a nM |
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| Citation |  Franco, FM; Jones, DE; Harris, PK; Han, Z; Wildman, SA; Jarvis, CM; Janetka, JW Structure-based discovery of small molecule hepsin and HGFA protease inhibitors: Evaluation of potency and selectivity derived from distinct binding pockets. Bioorg Med Chem23:2328-43 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Hepatocyte growth factor activator |
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| Name: | Hepatocyte growth factor activator |
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| Synonyms: | HGF activator | HGFA | HGFAC | HGFA_HUMAN | Hepatocyte growth factor activator | Hepatocyte growth factor activator long chain | Hepatocyte growth factor activator short chain |
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| Type: | PROTEIN |
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| Mol. Mass.: | 70690.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109514 |
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| Residue: | 655 |
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| Sequence: | MGRWAWVPSPWPPPGLGPFLLLLLLLLLLPRGFQPQPGGNRTESPEPNATATPAIPTILV
TSVTSETPATSAPEAEGPQSGGLPPPPRAVPSSSSPQAQALTEDGRPCRFPFRYGGRMLH
ACTSEGSAHRKWCATTHNYDRDRAWGYCVEATPPPGGPAALDPCASGPCLNGGSCSNTQD
PQSYHCSCPRAFTGKDCGTEKCFDETRYEYLEGGDRWARVRQGHVEQCECFGGRTWCEGT
RHTACLSSPCLNGGTCHLIVATGTTVCACPPGFAGRLCNIEPDERCFLGNGTGYRGVAST
SASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDNDERPWCYVVKDSALSWE
YCRLEACESLTRVQLSPDLLATLPEPASPGRQACGRRHKKRTFLRPRIIGGSSSLPGSHP
WLAAIYIGDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIE
KYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGW
GHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGG
PLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRIRPPRRLVAPS
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| BDBM50069125 |
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| n/a |
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| Name | BDBM50069125 |
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| Synonyms: | CHEMBL3403527 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H16N4O2S |
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| Mol. Mass. | 304.367 |
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| SMILES | Cc1ccc(cc1)S(=O)(=O)Nc1ccc(NC(N)=N)cc1 |
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| Structure | 
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