| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase |
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| Ligand | BDBM10877 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1466707 (CHEMBL3404500) |
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| Ki | >100000±n/a nM |
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| Citation |  Syrjänen, L; Kuuslahti, M; Tolvanen, M; Vullo, D; Parkkila, S; Supuran, CT Theß-carbonic anhydrase from the malaria mosquito Anopheles gambiae is highly inhibited by sulfonamides. Bioorg Med Chem23:2303-9 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase |
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| Name: | Carbonic anhydrase |
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| Synonyms: | Carbonate dehydratase | Carbonic anhydrase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 29919.95 |
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| Organism: | Anopheles gambiae |
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| Description: | ChEMBL_109570 |
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| Residue: | 255 |
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| Sequence: | MERILRGVMRYRHTTREQMVQEFRKVRDNPQPKAVFFTCMDSRMIPTRFTETHVGDMFVV
RNAGNLVPHAEHFQDEYFSCEPAALELGCVVNNIKHIIVCGHSDCKAMNLLYKLKDPEFA
SLDNRRISPLRAWLCEHANTSLAKFQNLKEIGLDKPLIFSSETPLRKFVAYIDPENNFAI
EDKLSQVNTLQQIENVASYGFLKRRLESHDLHIHALWFDIYTGDIYFFSRNSKRFIAIDE
SSIDRLLDEVRRYYS
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| BDBM10877 |
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| n/a |
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| Name | BDBM10877 |
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| Synonyms: | 4-(2-hydroxyethyl)benzene-1-sulfonamide | CHEMBL6784 | JMC522226 Compound 21 | JMC523116 Compound 21 | aromatic/heteroaromatic sulfonamide 22 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H11NO3S |
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| Mol. Mass. | 201.243 |
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| SMILES | NS(=O)(=O)c1ccc(CCO)cc1 |
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| Structure | 
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