| Reaction Details |
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 | Report a problem with these data |
| Target | Ubiquitin carboxyl-terminal hydrolase 10 |
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| Ligand | BDBM50069761 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1469497 (CHEMBL3412294) |
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| IC50 | 600±n/a nM |
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| Citation |  Ndubaku, C; Tsui, V Inhibiting the deubiquitinating enzymes (DUBs). J Med Chem58:1581-95 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Ubiquitin carboxyl-terminal hydrolase 10 |
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| Name: | Ubiquitin carboxyl-terminal hydrolase 10 |
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| Synonyms: | Deubiquitinating enzyme 10 | KIAA0190 | UBP10_HUMAN | USP10 | Ubiquitin carboxyl-terminal hydrolase 10 | Ubiquitin thioesterase 10 | Ubiquitin-specific-processing protease 10 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 87115.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109582 |
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| Residue: | 798 |
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| Sequence: | MALHSPQYIFGDFSPDEFNQFFVTPRSSVELPPYSGTVLCGTQAVDKLPDGQEYQRIEFG
VDEVIEPSDTLPRTPSYSISSTLNPQAPEFILGCTASKITPDGITKEASYGSIDCQYPGS
ALALDGSSNVEAEVLENDGVSGGLGQRERKKKKKRPPGYYSYLKDGGDDSISTEALVNGH
ANSAVPNSVSAEDAEFMGDMPPSVTPRTCNSPQNSTDSVSDIVPDSPFPGALGSDTRTAG
QPEGGPGADFGQSCFPAEAGRDTLSRTAGAQPCVGTDTTENLGVANGQILESSGEGTATN
GVELHTTESIDLDPTKPESASPPADGTGSASGTLPVSQPKSWASLFHDSKPSSSSPVAYV
ETKYSPPAISPLVSEKQVEVKEGLVPVSEDPVAIKIAELLENVTLIHKPVSLQPRGLINK
GNWCYINATLQALVACPPMYHLMKFIPLYSKVQRPCTSTPMIDSFVRLMNEFTNMPVPPK
PRQALGDKIVRDIRPGAAFEPTYIYRLLTVNKSSLSEKGRQEDAEEYLGFILNGLHEEML
NLKKLLSPSNEKLTISNGPKNHSVNEEEQEEQGEGSEDEWEQVGPRNKTSVTRQADFVQT
PITGIFGGHIRSVVYQQSSKESATLQPFFTLQLDIQSDKIRTVQDALESLVARESVQGYT
TKTKQEVEISRRVTLEKLPPVLVLHLKRFVYEKTGGCQKLIKNIEYPVDLEISKELLSPG
VKNKNFKCHRTYRLFAVVYHHGNSATGGHYTTDVFQIGLNGWLRIDDQTVKVINQYQVVK
PTAERTAYLLYYRRVDLL
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| BDBM50069761 |
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| n/a |
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| Name | BDBM50069761 |
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| Synonyms: | CHEMBL2391504 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H11F2N3 |
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| Mol. Mass. | 271.2647 |
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| SMILES | Fc1ccc(CNc2ncnc3ccc(F)cc23)cc1 |
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| Structure | 
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