| Reaction Details |
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 | Report a problem with these data |
| Target | Pantothenate kinase 3 |
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| Ligand | BDBM50071514 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1469804 (CHEMBL3413798) |
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| EC50 | 1510±n/a nM |
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| Citation |  Sharma, LK; Leonardi, R; Lin, W; Boyd, VA; Goktug, A; Shelat, AA; Chen, T; Jackowski, S; Rock, CO A high-throughput screen reveals new small-molecule activators and inhibitors of pantothenate kinases. J Med Chem58:1563-8 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Pantothenate kinase 3 |
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| Name: | Pantothenate kinase 3 |
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| Synonyms: | PANK3 | PANK3_HUMAN | Pantothenate kinase 3 | Pantothenic acid kinase 3 | hPanK3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41093.59 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109587 |
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| Residue: | 370 |
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| Sequence: | MKIKDAKKPSFPWFGMDIGGTLVKLSYFEPIDITAEEEQEEVESLKSIRKYLTSNVAYGS
TGIRDVHLELKDLTLFGRRGNLHFIRFPTQDLPTFIQMGRDKNFSTLQTVLCATGGGAYK
FEKDFRTIGNLHLHKLDELDCLVKGLLYIDSVSFNGQAECYYFANASEPERCQKMPFNLD
DPYPLLVVNIGSGVSILAVHSKDNYKRVTGTSLGGGTFLGLCSLLTGCESFEEALEMASK
GDSTQADKLVRDIYGGDYERFGLPGWAVASSFGNMIYKEKRESVSKEDLARATLVTITNN
IGSVARMCAVNEKINRVVFVGNFLRVNTLSMKLLAYALDYWSKGQLKALFLEHEGYFGAV
GALLGLPNFS
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| BDBM50071514 |
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| n/a |
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| Name | BDBM50071514 |
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| Synonyms: | CHEMBL3410241 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H17ClFN3OS |
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| Mol. Mass. | 389.874 |
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| SMILES | Fc1ccc(CC(=O)N2CCN(CC2)c2nc3c(Cl)cccc3s2)cc1 |
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| Structure | 
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