| Reaction Details |
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 | Report a problem with these data |
| Target | Krueppel-like factor 10 |
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| Ligand | BDBM50071809 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1467056 (CHEMBL3411253) |
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| IC50 | 10000±n/a nM |
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| Citation |  Khedkar, SA; Sun, X; Rigby, AC; Feinberg, MW Discovery of small molecule inhibitors to Krüppel-like factor 10 (KLF10): implications for modulation of T regulatory cell differentiation. J Med Chem58:1466-78 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Krueppel-like factor 10 |
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| Name: | Krueppel-like factor 10 |
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| Synonyms: | EGR-alpha | KLF10 | KLF10_HUMAN | Krueppel-like factor 10 | TGFB-inducible early growth response protein 1 | TIEG | TIEG | TIEG-1 | TIEG1 | Transforming growth factor-beta-inducible early growth response protein 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52579.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109571 |
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| Residue: | 480 |
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| Sequence: | MLNFGASLQQTAEERMEMISERPKESMYSWNKTAEKSDFEAVEALMSMSCSWKSDFKKYV
ENRPVTPVSDLSEEENLLPGTPDFHTIPAFCLTPPYSPSDFEPSQVSNLMAPAPSTVHFK
SLSDTAKPHIAAPFKEEEKSPVSAPKLPKAQATSVIRHTADAQLCNHQTCPMKAASILNY
QNNSFRRRTHLNVEAARKNIPCAAVSPNRSKCERNTVADVDEKASAALYDFSVPSSETVI
CRSQPAPVSPQQKSVLVSPPAVSAGGVPPMPVICQMVPLPANNPVVTTVVPSTPPSQPPA
VCPPVVFMGTQVPKGAVMFVVPQPVVQSSKPPVVSPNGTRLSPIAPAPGFSPSAAKVTPQ
IDSSRIRSHICSHPGCGKTYFKSSHLKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHR
RTHTGEKKFACPMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ
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| BDBM50071809 |
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| n/a |
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| Name | BDBM50071809 |
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| Synonyms: | CHEMBL1333704 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H10N4O5 |
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| Mol. Mass. | 290.2316 |
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| SMILES | Cc1cc(ccc1[N+]([O-])=O)C(=O)Nc1cnc(O)nc1O |
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| Structure | 
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