| Reaction Details |
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 | Report a problem with these data |
| Target | Kallikrein-7 |
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| Ligand | BDBM50073222 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1469259 (CHEMBL3413940) |
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| Ki | 50600±n/a nM |
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| Citation |  Arama, DP; Soualmia, F; Lisowski, V; Longevial, JF; Bosc, E; Maillard, LT; Martinez, J; Masurier, N; El Amri, C Pyrido-imidazodiazepinones as a new class of reversible inhibitors of human kallikrein 7. Eur J Med Chem93:202-13 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kallikrein-7 |
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| Name: | Kallikrein-7 |
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| Synonyms: | KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27535.05 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1469257 |
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| Residue: | 253 |
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| Sequence: | MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV
NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS
QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY
KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK
FTKWINDTMKKHR
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| BDBM50073222 |
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| n/a |
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| Name | BDBM50073222 |
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| Synonyms: | CHEMBL3125572 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H20N4O |
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| Mol. Mass. | 380.4418 |
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| SMILES | Cc1ccccc1C1=Nc2nc3ccccn3c2C(=O)[C@H](Cc2ccccc2)N1 |r,t:8| |
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| Structure | 
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