| Reaction Details |
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 | Report a problem with these data |
| Target | Oligo-1,6-glucosidase IMA1 |
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| Ligand | BDBM50018905 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1467867 (CHEMBL3412764) |
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| IC50 | 35000±n/a nM |
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| Citation |  Niaz, H; Kashtoh, H; Khan, JA; Khan, A; Wahab, AT; Alam, MT; Khan, KM; Perveen, S; Choudhary, MI Synthesis of diethyl 4-substituted-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylates as a new series of inhibitors against yeasta-glucosidase. Eur J Med Chem95:199-209 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Oligo-1,6-glucosidase IMA1 |
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| Name: | Oligo-1,6-glucosidase IMA1 |
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| Synonyms: | α-glucosidase | Alpha-glucosidase | Alpha-glucosidase (α-glucosidase) | IMA1 | MALX3_YEAST | Oligo-1,6-glucosidase |
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| Type: | Protein |
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| Mol. Mass.: | 68577.59 |
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| Organism: | Saccharomyces cerevisiae S288c (Baker's yeast) |
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| Description: | n/a |
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| Residue: | 589 |
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| Sequence: | MTISSAHPETEPKWWKEATFYQIYPASFKDSNDDGWGDMKGIASKLEYIKELGADAIWIS
PFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWF
KESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSYFGGSAWTFDEKTQEFYLRLFCS
TQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVVGLPDAPVVDKNSTWQS
SDPYTLNGPRIHEFHQEMNQFIRNRVKDGREIMTVGEMQHASDETKRLYTSASRHELSEL
FNFSHTDVGTSPLFRYNLVPFELKDWKIALAELFRYINGTDCWSTIYLENHDQPRSITRF
GDDSPKNRVISGKLLSVLLSALTGTLYVYQGQELGQINFKNWPVEKYEDVEIRNNYNAIK
EEHGENSEEMKKFLEAIALISRDHARTPMQWSREEPNAGFSGPSAKPWFYLNDSFREGIN
VEDEIKDPNSVLNFWKEALKFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYNNKTLFAA
LNFSSDATDFKIPNDDSSFKLEFGNYPKKEVDASSRTLKPWEGRIYISE
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| BDBM50018905 |
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| n/a |
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| Name | BDBM50018905 |
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| Synonyms: | 2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester | CHEMBL289347 | diethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22N2O6 |
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| Mol. Mass. | 374.3878 |
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| SMILES | CCOC([O-])=C1C(C(C(=[OH+])OCC)=C(C)N=C1C)c1cccc(c1)[N+]([O-])=O |w:3.3,c:15,t:12| |
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| Structure | 
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