| Reaction Details |
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 | Report a problem with these data |
| Target | Histone-lysine N-methyltransferase SUV39H1 |
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| Ligand | BDBM50396981 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1473655 (CHEMBL3421224) |
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| Ki | >20000±n/a nM |
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| Citation |  Kaniskan, HÜ; Konze, KD; Jin, J Selective inhibitors of protein methyltransferases. J Med Chem58:1596-629 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone-lysine N-methyltransferase SUV39H1 |
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| Name: | Histone-lysine N-methyltransferase SUV39H1 |
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| Synonyms: | H3-K9-HMTase 1 | Histone H3-K9 methyltransferase 1 | KMT1A | Lysine N-methyltransferase 1A | Position-effect variegation 3-9 homolog | SUV39H | SUV39H1 | SUV91_HUMAN | Su(var)3-9 homolog 1 | Suppressor of variegation 3-9 homolog 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47917.07 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1473655 |
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| Residue: | 412 |
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| Sequence: | MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLCDYKKIREQEYY
LVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLRRHHRSKTPRHLDPSLANYLVQ
KAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVAVG
CECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKG
IRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFD
LDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEE
LTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYLF
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| BDBM50396981 |
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| n/a |
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| Name | BDBM50396981 |
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| Synonyms: | CHEMBL2171174 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H22N6O5S |
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| Mol. Mass. | 398.437 |
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| SMILES | CNc1ncnc2n(cnc12)[C@@H]1O[C@H](CSCC[C@H](N)C(O)=O)[C@@H](O)[C@H]1O |r| |
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| Structure | 
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