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TargetSET domain-containing protein 8 (SetD8)
LigandBDBM50075099
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1473626
IC50 700±n/a nM
Citation Kaniskan HÜKonze KDJin J Selective inhibitors of protein methyltransferases. J Med Chem 58:1596-629 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
SET domain-containing protein 8 (SetD8)
Name:SET domain-containing protein 8 (SetD8)
Synonyms:N-lysine methyltransferase SETD8
Type:Enzyme
Mol. Mass.:42919.11
Organism:Homo sapiens (Human)
Description:Q9NQR1
Residue:393
Sequence:
MGEGGAAAALVAAAAAAAAAAAAVVAGQRRRRLGRRARCHGPGRAAGGKMSKPCAVEAAA
AAVAATAPGPEMVERRGPGRPRTDGENVFTGQSKIYSYMSPNKCSGMRFPLQEENSVTHH
EVKCQGKPLAGIYRKREEKRNAGNAVRSAMKSEEQKIKDARKGPLVPFPNQKSEAAEPPK
TPPSSCDSTNAAIAKQALKKPIKGKQAPRKKAQGKTQQNRKLTDFYPVRRSSRKSKAELQ
SEERKRIDELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKRE
ALYAQDPSTGCYMYYFQYLSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLI
LIASRDIAAGEELLYDYGDRSKASIEAHPWLKH
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  Blast E-value cutoff:
BDBM50075099
n/a
NameBDBM50075099
Synonyms:CHEMBL580421 | TCMDC-124224
TypeSmall organic molecule
Emp. Form.C14H11NO3
Mol. Mass.241.242
SMILESCC1(C)C(=O)N=C2C1=C(O)C(=O)c1ccccc21 |c:5,8|
Structure
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