| Reaction Details |
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 | Report a problem with these data |
| Target | N-lysine methyltransferase KMT5A |
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| Ligand | BDBM50075100 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1473626 (CHEMBL3420965) |
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| IC50 | 500±n/a nM |
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| Citation |  Kaniskan, HÜ; Konze, KD; Jin, J Selective inhibitors of protein methyltransferases. J Med Chem58:1596-629 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| N-lysine methyltransferase KMT5A |
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| Name: | N-lysine methyltransferase KMT5A |
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| Synonyms: | KMT5A | KMT5A_HUMAN | N-lysine methyltransferase SETD8 | PRSET7 | SET domain-containing protein 8 (SetD8) | SET07 | SET8 | SETD8 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42919.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9NQR1 |
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| Residue: | 393 |
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| Sequence: | MGEGGAAAALVAAAAAAAAAAAAVVAGQRRRRLGRRARCHGPGRAAGGKMSKPCAVEAAA
AAVAATAPGPEMVERRGPGRPRTDGENVFTGQSKIYSYMSPNKCSGMRFPLQEENSVTHH
EVKCQGKPLAGIYRKREEKRNAGNAVRSAMKSEEQKIKDARKGPLVPFPNQKSEAAEPPK
TPPSSCDSTNAAIAKQALKKPIKGKQAPRKKAQGKTQQNRKLTDFYPVRRSSRKSKAELQ
SEERKRIDELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKRE
ALYAQDPSTGCYMYYFQYLSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLI
LIASRDIAAGEELLYDYGDRSKASIEAHPWLKH
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| BDBM50075100 |
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| n/a |
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| Name | BDBM50075100 |
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| Synonyms: | CHEMBL3414625 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H12N2O2S |
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| Mol. Mass. | 284.333 |
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| SMILES | Cc1nc2c(s1)C(=O)C\C(=N/c1ccc(C)cc1)C2=O |
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| Structure | 
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