| Reaction Details |
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 | Report a problem with these data |
| Target | Testis-specific serine/threonine-protein kinase 3 |
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| Ligand | BDBM50075731 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1473799 (CHEMBL3418524) |
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| IC50 | 420±n/a nM |
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| Citation |  Ellis, JM; Altman, MD; Bass, A; Butcher, JW; Byford, AJ; Donofrio, A; Galloway, S; Haidle, AM; Jewell, J; Kelly, N; Leccese, EK; Lee, S; Maddess, M; Miller, JR; Moy, LY; Osimboni, E; Otte, RD; Reddy, MV; Spencer, K; Sun, B; Vincent, SH; Ward, GJ; Woo, GH; Yang, C; Houshyar, H; Northrup, AB Overcoming mutagenicity and ion channel activity: optimization of selective spleen tyrosine kinase inhibitors. J Med Chem58:1929-39 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Testis-specific serine/threonine-protein kinase 3 |
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| Name: | Testis-specific serine/threonine-protein kinase 3 |
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| Synonyms: | SPOGA3 | SPOGA3 | STK22C | Serine/threonine-protein kinase 22C | TSK-3 | TSSK-3 | TSSK3 | TSSK3_HUMAN | Testis-specific kinase 3 | Testis-specific serine/threonine-protein kinase 3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 30102.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109599 |
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| Residue: | 268 |
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| Sequence: | MEDFLLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQ
IVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVE
AIRYCHGCGVAHRDLKCENALLQGFNLKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPEV
LQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQD
LLKRLLEPDMILRPSIEEVSWHPWLAST
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| BDBM50075731 |
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| n/a |
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| Name | BDBM50075731 |
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| Synonyms: | CHEMBL3415608 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22N6O |
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| Mol. Mass. | 350.4176 |
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| SMILES | N[C@H]1CCCC[C@H]1Nc1cnc(C(N)=O)c(c1)-c1nc2ccccc2[nH]1 |r| |
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| Structure | 
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