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TargetSerum albumin
LigandBDBM50078151
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1472594
Ki<30±n/a nM
Citation Bruncko MWang LSheppard GSPhillips DCTahir SKXue JErickson SFidanze SFry EHasvold LJenkins GJJin SJudge RAKovar PJMadar DNimmer PPark CPetros AMRosenberg SHSmith MLSong XSun CTao ZFWang XXiao YZhang HTse CLeverson JDElmore SWSouers AJ Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivity. J Med Chem 58:2180-94 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Serum albumin
Name:Serum albumin
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:69362.94
Organism:Homo sapiens (Human)
Description:ChEMBL_1509401
Residue:609
Sequence:
MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPF
EDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEP
ERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLF
FAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAV
ARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLK
ECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYAR
RHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFE
QLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVV
LNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTL
SEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLV
AASQAALGL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50078151
n/a
NameBDBM50078151
Synonyms:CHEMBL3417691
TypeSmall organic molecule
Emp. Form.C29H25NO3
Mol. Mass.435.5137
SMILESCc1ccccc1-c1cccc2c(CCCOc3cccc4ccccc34)c([nH]c12)C(O)=O
Structure
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