| Reaction Details |
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 | Report a problem with these data |
| Target | Integrin-linked protein kinase |
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| Ligand | BDBM50078207 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1470576 (CHEMBL3419802) |
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| Kd | 13100±n/a nM |
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| Citation |  Yan, R; Chuang, HC; Kapuriya, N; Chou, CC; Lai, PT; Chang, HW; Yang, CN; Kulp, SK; Chen, CS Exploitation of the ability of¿-tocopherol to facilitate membrane co-localization of Akt and PHLPP1 to develop PHLPP1-targeted Akt inhibitors. J Med Chem58:2290-8 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrin-linked protein kinase |
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| Name: | Integrin-linked protein kinase |
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| Synonyms: | ILK | ILK1 | ILK2 | ILK_HUMAN | Integrin-linked protein kinase (ILK) | Serine/threonine-protein kinase ILK-1 |
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| Type: | Protein |
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| Mol. Mass.: | 51429.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13418 |
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| Residue: | 452 |
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| Sequence: | MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARI
NVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLV
ANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNG
TLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECP
RLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALD
MARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEA
LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH
VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK
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| BDBM50078207 |
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| n/a |
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| Name | BDBM50078207 |
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| Synonyms: | CHEMBL3414688 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H24BrNO3S |
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| Mol. Mass. | 390.336 |
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| SMILES | CC(C)CCCC1(C)CCc2cc(cc(Br)c2O1)S(N)(=O)=O |
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| Structure | 
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