| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor delta |
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| Ligand | BDBM50383373 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1472809 (CHEMBL3419309) |
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| IC50 | 155±n/a nM |
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| Citation |  Kaupang, Å; Paulsen, SM; Steindal, CC; Ravna, AW; Sylte, I; Halvorsen, TG; Thoresen, GH; Hansen, TV Synthesis, biological evaluation and molecular modeling studies of the PPARß/d antagonist CC618. Eur J Med Chem94:229-36 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor delta |
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| Name: | Peroxisome proliferator-activated receptor delta |
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| Synonyms: | NR1C2 | NUC1 | NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR delta | PPAR-beta | PPARB | PPARD | PPARD_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor beta | Peroxisome proliferator-activated receptor delta |
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| Type: | Enzyme |
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| Mol. Mass.: | 49910.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q03181 |
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| Residue: | 441 |
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| Sequence: | MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQM
GCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKK
NRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSK
HIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKE
ISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNK
DGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGD
RPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRI
KKTETETSLHPLLQEIYKDMY
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| BDBM50383373 |
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| n/a |
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| Name | BDBM50383373 |
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| Synonyms: | CHEMBL592652 | GSK0660 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H18N2O5S2 |
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| Mol. Mass. | 418.487 |
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| SMILES | COC(=O)c1sccc1S(=O)(=O)Nc1ccc(Nc2ccccc2)cc1OC |
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| Structure | 
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