| Reaction Details |
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 | Report a problem with these data |
| Target | Cell division protein FtsZ |
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| Ligand | BDBM50439496 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1470464 (CHEMBL3419181) |
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| IC50 | 38000±n/a nM |
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| Citation |  Li, X; Ma, S Advances in the discovery of novel antimicrobials targeting the assembly of bacterial cell division protein FtsZ. Eur J Med Chem95:1-15 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cell division protein FtsZ |
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| Name: | Cell division protein FtsZ |
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| Synonyms: | FTSZ_STAAU | ftsZ |
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| Type: | Protein |
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| Mol. Mass.: | 41023.36 |
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| Organism: | Staphylococcus aureus |
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| Description: | P0A031 |
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| Residue: | 390 |
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| Sequence: | MLEFEQGFNHLATLKVIGVGGGGNNAVNRMIDHGMNNVEFIAINTDGQALNLSKAESKIQ
IGEKLTRGLGAGANPEIGKKAAEESREQIEDAIQGADMVFVTSGMGGGTGTGAAPVVAKI
AKEMGALTVGVVTRPFSFEGRKRQTQAAAGVEAMKAAVDTLIVIPNDRLLDIVDKSTPMM
EAFKEADNVLRQGVQGISDLIAVSGEVNLDFADVKTIMSNQGSALMGIGVSSGENRAVEA
AKKAISSPLLETSIVGAQGVLMNITGGESLSLFEAQEAADIVQDAADEDVNMIFGTVINP
ELQDEIVVTVIATGFDDKPTSHGRKSGSTGFGTSVNTSSNATSKDESFTSNSSNAQATDS
VSERTHTTKEDDIPSFIRNREERRSRRTRR
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| BDBM50439496 |
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| n/a |
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| Name | BDBM50439496 |
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| Synonyms: | CHEMBL2418096 | US9169182, J23 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18Cl2O4 |
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| Mol. Mass. | 369.239 |
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| SMILES | COc1cc(C\C=C(\Cl)Cc2cc(O)cc(O)c2)c(OC)cc1Cl |
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| Structure | 
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