| Reaction Details |
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 | Report a problem with these data |
| Target | Matrix protein 2 [1-96] |
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| Ligand | BDBM50079996 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1471017 (CHEMBL3420249) |
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| IC50 | 17200±n/a nM |
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| Citation |  Rey-Carrizo, M; Gazzarrini, S; Llabrés, S; Frigolé-Vivas, M; Juárez-Jiménez, J; Font-Bardia, M; Naesens, L; Moroni, A; Luque, FJ; Vázquez, S New polycyclic dual inhibitors of the wild type and the V27A mutant M2 channel of the influenza A virus with unexpected binding mode. Eur J Med Chem96:318-29 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Matrix protein 2 [1-96] |
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| Name: | Matrix protein 2 [1-96] |
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| Synonyms: | M | M2_I72A2 | Matrix protein 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 11051.96 |
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| Organism: | Influenza A virus |
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| Description: | ChEMBL_1453980 |
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| Residue: | 96 |
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| Sequence: | MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRFFEHGLK
RGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIEL
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| BDBM50079996 |
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| n/a |
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| Name | BDBM50079996 |
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| Synonyms: | CHEMBL3415948 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H21N |
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| Mol. Mass. | 227.3446 |
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| SMILES | [H][C@]12[C@@]3([H])[C@@]4([H])[C@@]1([H])[C@]1([H])[C@@]5([H])CNC[C@@]5([H])[C@@]4([H])[C@@]4([H])[C@]3([H])CC[C@]2([H])[C@@]14[H] |r,TLB:21:19:8:25.1,2:1:17.19.4:8,25:27:4.6:10.15,1:2:17:8.27.6,10:8:17:21.2,10:8:17.19.4:25.1,14:15:19.27:4.6,THB:12:10:19.27:4.6,21:19:4.6:10.15,23:21:17:8.27.6,2:4:8:25.1,2:4:19.27:10.15,25:27:17:21.2,24:25:17.19.4:8,1:6:17:21.2,1:6:19.27:10.15| |
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| Structure | 
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