| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
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| Ligand | BDBM50080870 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1475316 (CHEMBL3425213) |
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| IC50 | 32020±n/a nM |
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| Citation |  Valente, S; Rodriguez, V; Mercurio, C; Vianello, P; Saponara, B; Cirilli, R; Ciossani, G; Labella, D; Marrocco, B; Ruoppolo, G; Botrugno, OA; Dessanti, P; Minucci, S; Mattevi, A; Varasi, M; Mai, A Pure Diastereomers of a Tranylcypromine-Based LSD1 Inhibitor: Enzyme Selectivity and In-Cell Studies. ACS Med Chem Lett6:173-7 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Amine oxidase [flavin-containing] B |
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| Name: | Amine oxidase [flavin-containing] B |
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| Synonyms: | AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB) |
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| Type: | Protein |
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| Mol. Mass.: | 58768.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P27338 |
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| Residue: | 520 |
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| Sequence: | MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
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| BDBM50080870 |
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| n/a |
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| Name | BDBM50080870 |
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| Synonyms: | CHEMBL3421673 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H28ClN3O3 |
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| Mol. Mass. | 465.972 |
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| SMILES | Cl.N[C@@H]1C[C@H]1c1ccc(NC(=O)[C@H](Cc2ccccc2)NC(=O)OCc2ccccc2)cc1 |r| |
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| Structure | 
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