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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cannabinoid receptor 1 | ||
| Ligand | BDBM50082768 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1475938 (CHEMBL3425335) | ||
| EC50 | 2512±n/a nM | ||
| Citation |  Manera, C; Malfitano, AM; Parkkari, T; Lucchesi, V; Carpi, S; Fogli, S; Bertini, S; Laezza, C; Ligresti, A; Saccomanni, G; Savinainen, JR; Ciaglia, E; Pisanti, S; Gazzerro, P; Di Marzo, V; Nieri, P; Macchia, M; Bifulco, M New quinolone- and 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity. Eur J Med Chem97:10-8 (2015) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cannabinoid receptor 1 | |||
| Name: | Cannabinoid receptor 1 | ||
| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 52856.55 | ||
| Organism: | Rattus norvegicus (rat) | ||
| Description: | P20272 | ||
| Residue: | 473 | ||
| Sequence: |
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| BDBM50082768 | |||
| n/a | |||
| Name | BDBM50082768 | ||
| Synonyms: | CHEMBL3422788 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H30N2O2 | ||
| Mol. Mass. | 354.4858 | ||
| SMILES | CCCCCn1c2ccccc2cc(C(=O)NC2CCC(C)CC2)c1=O |(4.01,-7.39,;4.01,-6.16,;2.67,-5.39,;2.67,-3.85,;1.33,-3.08,;1.33,-1.54,;,-.77,;-1.33,-1.54,;-2.68,-.77,;-2.68,.77,;-1.33,1.54,;,.77,;1.33,1.54,;2.66,.77,;3.99,1.54,;5.06,.93,;3.99,3.08,;5.33,3.86,;5.33,5.4,;6.66,6.17,;7.99,5.4,;9.06,6.01,;7.99,3.86,;6.66,3.09,;2.66,-.77,;3.73,-1.38,)| | ||
| Structure | 
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