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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cannabinoid receptor 1 | ||
| Ligand | BDBM50082776 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1475932 (CHEMBL3425329) | ||
| Ki | 800±n/a nM | ||
| Citation |  Manera, C; Malfitano, AM; Parkkari, T; Lucchesi, V; Carpi, S; Fogli, S; Bertini, S; Laezza, C; Ligresti, A; Saccomanni, G; Savinainen, JR; Ciaglia, E; Pisanti, S; Gazzerro, P; Di Marzo, V; Nieri, P; Macchia, M; Bifulco, M New quinolone- and 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity. Eur J Med Chem97:10-8 (2015) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cannabinoid receptor 1 | |||
| Name: | Cannabinoid receptor 1 | ||
| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 52868.96 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P21554 | ||
| Residue: | 472 | ||
| Sequence: |
| ||
| BDBM50082776 | |||
| n/a | |||
| Name | BDBM50082776 | ||
| Synonyms: | CHEMBL3422785 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H31N3O3 | ||
| Mol. Mass. | 397.5105 | ||
| SMILES | CC1CCC(CC1)NC(=O)c1cc2ccccc2n(CCN2CCOCC2)c1=O |(9.06,6.01,;7.99,5.4,;6.66,6.17,;5.33,5.4,;5.33,3.86,;6.66,3.09,;7.99,3.86,;3.99,3.08,;3.99,1.54,;5.06,.93,;2.66,.77,;1.33,1.54,;,.77,;-1.33,1.54,;-2.68,.77,;-2.68,-.77,;-1.33,-1.54,;,-.77,;1.33,-1.54,;1.33,-3.08,;2.67,-3.85,;2.67,-5.39,;4.01,-6.16,;4.01,-7.7,;2.67,-8.47,;1.34,-7.7,;1.34,-6.16,;2.66,-.77,;3.73,-1.38,)| | ||
| Structure | 
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