| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50087839 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1478283 (CHEMBL3428523) |
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| EC50 | 10000±n/a nM |
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| Citation |  Burford, NT; Livingston, KE; Canals, M; Ryan, MR; Budenholzer, LM; Han, Y; Shang, Y; Herbst, JJ; O'Connell, J; Banks, M; Zhang, L; Filizola, M; Bassoni, DL; Wehrman, TS; Christopoulos, A; Traynor, JR; Gerritz, SW; Alt, A Discovery, synthesis, and molecular pharmacology of selective positive allosteric modulators of thed-opioid receptor. J Med Chem58:4220-9 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44789.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35372 |
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| Residue: | 400 |
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| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50087839 |
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| n/a |
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| Name | BDBM50087839 |
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| Synonyms: | CHEMBL3426801 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H34O5 |
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| Mol. Mass. | 486.5987 |
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| SMILES | CC1(C)CC(=O)C2=C(C1)OC1=C(C2c2ccc(OCc3ccccc3CO)cc2)C(=O)CC(C)(C)C1 |c:6,11| |
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| Structure | 
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