| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase CDC14A |
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| Ligand | BDBM50087856 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1476059 (CHEMBL3428555) |
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| pH | 7±n/a |
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| IC50 | 7200±n/a nM |
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| Comments | extracted |
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| Citation |  He, Y; Guo, X; Yu, ZH; Wu, L; Gunawan, AM; Zhang, Y; Dixon, JE; Zhang, ZY A potent and selective inhibitor for the UBLCP1 proteasome phosphatase. Bioorg Med Chem23:2798-809 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein phosphatase CDC14A |
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| Name: | Dual specificity protein phosphatase CDC14A |
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| Synonyms: | 3.1.3.16 | 3.1.3.48 | CC14A_HUMAN | CDC14 cell division cycle 14 homolog A | CDC14A |
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| Type: | n/a |
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| Mol. Mass.: | 66598.40 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9UNH5 |
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| Residue: | 594 |
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| Sequence: | MAAESGELIGACEFMKDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMV
YRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLS
GSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDF
NWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDA
GFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFT
HAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSEGSINKILSGLD
DMSIGGNLSKTQNMERFGEDNLEDDDVEMKNGITQGDKLRALKSQRQPRTSPSCAFRSDD
TKGHPRAVSQPFRLSSSLQGSAVTLKTSKMALSPSATAKRINRTSLSSGATVRSFSINSR
LASSLGNLNAATDDPENKKTSSSSKAGFTASPFTNLLNGSSQPTTRNYPELNNNQYNRSS
NSNGGNLNSPPGPHSAKTEEHTTILRPSYTGLSSSSARFLSRSIPSLQSEYVHY
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| BDBM50087856 |
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| n/a |
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| Name | BDBM50087856 |
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| Synonyms: | CHEMBL3426913 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H30F3NO6 |
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| Mol. Mass. | 533.5361 |
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| SMILES | CCCCC(Oc1cc(O)c(cc1C#Cc1ccccc1OC(F)(F)F)C(O)=O)C(=O)NC1CCCCC1 |
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| Structure | 
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