| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50353747 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1481943 (CHEMBL3541169) |
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| Ki | 1.3±n/a nM |
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| Citation |  Chimalakonda, KC; Seely, KA; Bratton, SM; Brents, LK; Moran, CL; Endres, GW; James, LP; Hollenberg, PF; Prather, PL; Radominska-Pandya, A; Moran, JH Cytochrome P450-mediated oxidative metabolism of abused synthetic cannabinoids found in K2/Spice: identification of novel cannabinoid receptor ligands. Drug Metab Dispos40:2174-84 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_MOUSE | Cannabinoid CB1 receptor | Cannabinoid receptor | Cnr1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 52842.52 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P47746 |
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| Residue: | 473 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEDNIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50353747 |
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| n/a |
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| Name | BDBM50353747 |
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| Synonyms: | CHEMBL561013 | JWH-018 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H23NO |
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| Mol. Mass. | 341.4455 |
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| SMILES | CCCCCn1cc(C(=O)c2cccc3ccccc23)c2ccccc12 |
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| Structure | 
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