| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier organic anion transporter family member 2B1 |
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| Ligand | BDBM50442881 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1494639 (CHEMBL3529889) |
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| IC50 | 4500±n/a nM |
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| Citation |  Köck, K; Xie, Y; Hawke, RL; Oberlies, NH; Brouwer, KL Interaction of silymarin flavonolignans with organic anion-transporting polypeptides. Drug Metab Dispos41:958-65 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier organic anion transporter family member 2B1 |
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| Name: | Solute carrier organic anion transporter family member 2B1 |
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| Synonyms: | KIAA0880 | OATP-B | OATP-RP2 | OATP2B1 | OATPB | OATPRP2 | Organic anion transporter B | Organic anion transporter polypeptide-related protein 2 | SLC21A9 | SLCO2B1 | SO2B1_HUMAN | Solute carrier family 21 member 9 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 76729.07 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1488531 |
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| Residue: | 709 |
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| Sequence: | MGPRIGPAGEVPQVPDKETKATMGTENTPGGKASPDPQDVRPSVFHNIKLFVLCHSLLQL
AQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSYFGSRVHRPRMIGY
GAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSAPASAPSNGNCSSY
TETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGL
AFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKE
MPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVF
PRVLLQTLRHPIFLLVVLSQVCLSSMAAGMAIFLPKFLERQFSITASYANLLIGCLSFPS
VIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGITHQTSAH
PGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCS
CVVEGNPVLAGSCDSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVG
IQFMFLRILAWMPSPVIHGSAIDTTCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFFFKT
GSVICFALVLAVLRQQDKEARTKESRSSPAVEQQLLVSGPGKKPEDSRV
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| BDBM50442881 |
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| n/a |
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| Name | BDBM50442881 |
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| Synonyms: | SILYBIN A |
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| Type | Small organic molecule |
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| Emp. Form. | C25H22O10 |
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| Mol. Mass. | 482.4362 |
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| SMILES | COc1cc(ccc1O)[C@H]1Oc2cc(ccc2O[C@@H]1CO)[C@H]1Oc2cc(O)cc(O)c2C(O)C1=O |r| |
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| Structure | 
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