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TargetSolute carrier organic anion transporter family member 2B1
LigandBDBM50088491
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1494639
IC50 800±n/a nM
Citation Köck KXie YHawke RLOberlies NHBrouwer KL Interaction of silymarin flavonolignans with organic anion-transporting polypeptides. Drug Metab Dispos 41:958-65 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Solute carrier organic anion transporter family member 2B1
Name:Solute carrier organic anion transporter family member 2B1
Synonyms:KIAA0880 | OATP-B | OATP-RP2 | OATP2B1 | OATPB | OATPRP2 | Organic anion transporter B | Organic anion transporter polypeptide-related protein 2 | SLC21A9 | SLCO2B1 | Solute carrier family 21 member 9
Type:PROTEIN
Mol. Mass.:76729.07
Organism:Homo sapiens (Human)
Description:ChEMBL_1488531
Residue:709
Sequence:
MGPRIGPAGEVPQVPDKETKATMGTENTPGGKASPDPQDVRPSVFHNIKLFVLCHSLLQL
AQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSYFGSRVHRPRMIGY
GAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSAPASAPSNGNCSSY
TETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGL
AFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKE
MPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVF
PRVLLQTLRHPIFLLVVLSQVCLSSMAAGMAIFLPKFLERQFSITASYANLLIGCLSFPS
VIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGITHQTSAH
PGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCS
CVVEGNPVLAGSCDSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVG
IQFMFLRILAWMPSPVIHGSAIDTTCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFFFKT
GSVICFALVLAVLRQQDKEARTKESRSSPAVEQQLLVSGPGKKPEDSRV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50088491
n/a
NameBDBM50088491
Synonyms:SILYBIN B | Silybin B
TypeSmall organic molecule
Emp. Form.C25H22O10
Mol. Mass.482.4362
SMILESCOc1cc(ccc1O)[C@@H]1Oc2cc(ccc2O[C@H]1CO)[C@H]1Oc2cc(O)cc(O)c2C(=O)[C@@H]1O |r|
Structure
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