| Reaction Details |
|---|
 | Report a problem with these data |
| Target | UDP-glucuronosyltransferase 1A10 |
|---|
| Ligand | BDBM50088505 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1491709 (CHEMBL3536901) |
|---|
| Ki | 242000±n/a nM |
|---|
| Citation |  Gao, C; Zhang, H; Guo, Z; You, T; Chen, X; Zhong, D Mechanistic studies on the absorption and disposition of scutellarin in humans: selective OATP2B1-mediated hepatic uptake is a likely key determinant for its unique pharmacokinetic characteristics. Drug Metab Dispos40:2009-20 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| UDP-glucuronosyltransferase 1A10 |
|---|
| Name: | UDP-glucuronosyltransferase 1A10 |
|---|
| Synonyms: | GNT1 | UD110_HUMAN | UDP-glucuronosyltransferase 1-10 | UDP-glucuronosyltransferase 1-J | UDP-glucuronosyltransferase 1A10 | UDPGT 1-10 | UGT-1J | UGT1 | UGT1*10 | UGT1-10 | UGT1.10 | UGT1A10 | UGT1J |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 59817.97 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1491709 |
|---|
| Residue: | 530 |
|---|
| Sequence: | MARAGWTSPVPLCVCLLLTCGFAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMP
EVSWQLERSLNCTVKTYSTSYTLEDQNREFMVFAHAQWKAQAQSIFSLLMSSSSGFLDLF
FSHCRSLFNDRKLVEYLKESSFDAVFLDPFDTCGLIVAKYFSLPSVVFTRGIFCHHLEEG
AQCPAPLSYVPNDLLGFSDAMTFKERVWNHIVHLEDHLFCQYLFRNALEIASEILQTPVT
AYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIV
VFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGH
PMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDL
ENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTW
YQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
|
|
|
|---|
| BDBM50088505 |
|---|
| n/a |
|---|
| Name | BDBM50088505 |
|---|
| Synonyms: | CHEMBL3542370 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H18O12 |
|---|
| Mol. Mass. | 462.3604 |
|---|
| SMILES | O[C@H]1[C@H](Oc2c(O)cc3oc(cc(=O)c3c2O)-c2ccc(O)cc2)O[C@@H]([C@@H](O)[C@@H]1O)C(O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
