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TargetSulfotransferase 1A1 (SULT1A1)
LigandBDBM50187243
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1484210
Kd 500±n/a nM
Citation Rohn KJCook ITLeyh TSKadlubar SAFalany CN Potent inhibition of human sulfotransferase 1A1 by 17a-ethinylestradiol: role of 3'-phosphoadenosine 5'-phosphosulfate binding and structural rearrangements in regulating inhibition and activity. Drug Metab Dispos 40:1588-95 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sulfotransferase 1A1 (SULT1A1)
Name:Sulfotransferase 1A1 (SULT1A1)
Synonyms:Aryl sulfotransferase 1 | HAST1/HAST2 | P-PST 1 | Phenol sulfotransferase 1 | Phenol-sulfating phenol sulfotransferase 1 | ST1A1 | ST1A3 | STP | STP1 | SULT1A1 | Sulfotransferase 1A1 | Thermostable phenol sulfotransferase | Ts-PST
Type:Enzyme
Mol. Mass.:34165.45
Organism:Homo sapiens (Human)
Description:P50225
Residue:295
Sequence:
MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDM
IYQGGDLEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLD
QKVKVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWW
ELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNY
TTVPQEFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL
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  Blast E-value cutoff:
BDBM50187243
n/a
NameBDBM50187243
Synonyms:17-ethinyl-3,17-estradiol | 17-ethinyl-3,17-oestradiol | 17-ethinylestradiol | 17alpha-Ethinyl estradiol | 17alpha-ethynylestra-1,3,5(10)-triene-3,17beta-diol | 17alpha-ethynylestradiol | CHEMBL691 | ETHINYL ESTRADIOL | Ethinylestradiol | Ethynyl estradiol | ethinyloestradiol
TypeSmall organic molecule
Emp. Form.C20H24O2
Mol. Mass.296.4034
SMILESC[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CC[C@@]2(O)C#C |r|
Structure
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