| Reaction Details |
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 | Report a problem with these data |
| Target | Sulfotransferase 1A1 |
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| Ligand | BDBM17292 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1484210 (CHEMBL3537871) |
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| Kd | 2300±n/a nM |
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| Citation |  Rohn, KJ; Cook, IT; Leyh, TS; Kadlubar, SA; Falany, CN Potent inhibition of human sulfotransferase 1A1 by 17a-ethinylestradiol: role of 3'-phosphoadenosine 5'-phosphosulfate binding and structural rearrangements in regulating inhibition and activity. Drug Metab Dispos40:1588-95 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sulfotransferase 1A1 |
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| Name: | Sulfotransferase 1A1 |
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| Synonyms: | Aryl sulfotransferase 1 | HAST1/HAST2 | P-PST 1 | Phenol sulfotransferase 1 | Phenol-sulfating phenol sulfotransferase 1 | ST1A1 | ST1A1_HUMAN | ST1A3 | STP | STP | STP1 | SULT1A1 | Sulfotransferase 1A1 | Sulfotransferase 1A1 (SULT1A1) | Thermostable phenol sulfotransferase | Ts-PST |
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| Type: | Enzyme |
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| Mol. Mass.: | 34165.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P50225 |
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| Residue: | 295 |
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| Sequence: | MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDM
IYQGGDLEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLD
QKVKVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWW
ELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNY
TTVPQEFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL
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| BDBM17292 |
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| n/a |
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| Name | BDBM17292 |
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| Synonyms: | (1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2,4,6-triene-5,14-diol | 17 beta-Estradiol | 17α-ethinylestradiol | 17beta-estradiol (E2) | CHEMBL135 | CS336 | ESTRADIOL | Estradiol-17 alpha | Ovocyclin | US9034854, E2 | US9040509, E2 | US9422324, E2 | US9561238, E2 | [2,4,6,7-3H]-17beta-estradiol | [2,4,6,7-3H]-E2 | [3H]-estradiol | [3H]]estradiol |
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| Type | Steroid |
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| Emp. Form. | C18H24O2 |
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| Mol. Mass. | 272.382 |
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| SMILES | [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H] |
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| Structure | 
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