| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 15 member 1 |
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| Ligand | BDBM5025 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1488840 (CHEMBL3534498) |
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| IC50 | 10700000±n/a nM |
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| Citation |  Hu, Y; Chen, X; Smith, DE Species-dependent uptake of glycylsarcosine but not oseltamivir in Pichia pastoris expressing the rat, mouse, and human intestinal peptide transporter PEPT1. Drug Metab Dispos40:1328-35 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 15 member 1 |
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| Name: | Solute carrier family 15 member 1 |
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| Synonyms: | Intestinal H(+)/peptide cotransporter | Oligopeptide transporter, small intestine isoform | Pept1 | Peptide transporter 1 | Proton-coupled dipeptide cotransporter | S15A1_MOUSE | Slc15a1 | Solute carrier family 15 member 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 78568.93 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_104655 |
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| Residue: | 709 |
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| Sequence: | MGMSKSRGCFGYPLSIFFIVVNEFCERFSYYGMRALLVLYFRNFLGWDDNLSTAIYHTFV
ALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVISVSSINDLTDHDHNGSPDSLPV
HVALSMVGLALIALGTGGIKPCVSAFGGDQFEEGQEKQRNRFFSIFYLAINGGSLLSTII
TPILRVQQCGIHSQQACYPLAFGVPAALMAVALIVFVLGSGMYKKFQPQGNIMGKVAKCI
GFAIKNRFRHRSKAYPKREHWLDWAKEKYDERLISQIKMVTKVMFLYIPLPMFWALFDQQ
GSRWTLQATTMNGKIGAIEIQPDQMQTVNAILIVIMVPIVDAVVYPLIAKCGFNFTSLKK
MTVGMFLASMAFVVAAIVQVEIDKTLPVFPGGNQVQIKVLNIGNNNMTVHFPGNSVTLAQ
MSQTDTFMTFDIDKLTSINISSSGSPGVTTVAHDFEQGHRHTLLVWNPSQYRVVKDGLNQ
KPEKGENGIRFVNTLNEMVTIKMSGKVYENVTSHNASGYQFFPSGEKQYTINTTAVAPTC
LTDFKSSNLDFGSAYTYVIRRASDGCLEVKEFEDIPPNTVNMALQIPQYFLLTCGEVVFS
VTGLEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLIVAGAGHFPKQWAEYILFASLLLVV
CVIFAIMARFYTYINPAEIEAQFDEDEKKKGIGKENPYSSLEPVSQTNM
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| BDBM5025 |
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| n/a |
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| Name | BDBM5025 |
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| Synonyms: | Oseltamivir | US10919856, POSITIVE CONTROL | ethyl (3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C16H28N2O4 |
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| Mol. Mass. | 312.4045 |
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| SMILES | [H][C@@]1(OC(CC)CC)C=C(C[C@H](N)[C@H]1NC(C)=O)C(=O)OCC |r,c:8| |
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| Structure | 
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