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TargetUDP-glucuronosyltransferase 2B7
LigandBDBM50088511
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1481837 (CHEMBL3539958)
Ki 162000±n/a nM
Citation Sneitz, N; Vahermo, M; Mosorin, J; Laakkonen, L; Poirier, D; Finel, M Regiospecificity and stereospecificity of human UDP-glucuronosyltransferases in the glucuronidation of estriol, 16-epiestriol, 17-epiestriol, and 13-epiestradiol. Drug Metab Dispos41:582-91 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
UDP-glucuronosyltransferase 2B7
Name:UDP-glucuronosyltransferase 2B7
Synonyms:2.4.1.17 | 3,4-catechol estrogen-specific UDPGT | UD2B7_HUMAN | UDP-glucuronosyltransferase 2B7 | UDP-glucuronosyltransferase 2B9 | UDPGT 2B7 | UDPGT 2B9 | UDPGTh-2 | UGT2B7 | UGTB2B9 | Uridine-5'-diphosphoglucuronosyltransferase 2B7
Type:Enzyme
Mol. Mass.:60705.98
Organism:Homo sapiens (Human)
Description:P16662
Residue:529
Sequence:
MSVKWTSVILLIQLSFCFSSGNCGKVLVWAAEYSHWMNIKTILDELIQRGHEVTVLASSA
SILFDPNNSSALKIEIYPTSLTKTELENFIMQQIKRWSDLPKDTFWLYFSQVQEIMSIFG
DITRKFCKDVVSNKKFMKKVQESRFDVIFADAIFPCSELLAELFNIPFVYSLSFSPGYTF
EKHSGGFIFPPSYVPVVMSELTDQMTFMERVKNMIYVLYFDFWFEIFDMKKWDQFYSEVL
GRPTTLSETMGKADVWLIRNSWNFQFPYPLLPNVDFVGGLHCKPAKPLPKEMEDFVQSSG
ENGVVVFSLGSMVSNMTEERANVIASALAQIPQKVLWRFDGNKPDTLGLNTRLYKWIPQN
DLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFADQPDNIAHMKARGAAVRVDFNTM
SSTDLLNALKRVINDPSYKENVMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAA
HDLTWFQYHSLDVIGFLLVCVATVIFIVTKCCLFCFWKFARKAKKGKND
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50088511
n/a
NameBDBM50088511
Synonyms:CHEBI:87620 | Epiestriol | Epioestriol
TypeSmall organic molecule
Emp. Form.C18H24O3
Mol. Mass.288.3814
SMILES[H][C@@]12C[C@H](O)[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H] |r|
Structure
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