| Reaction Details |
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 | Report a problem with these data |
| Target | Carboxypeptidase B |
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| Ligand | BDBM50089691 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1496384 (CHEMBL3580150) |
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| IC50 | 1.000000±n/a nM |
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| Citation |  Halland, N; Brönstrup, M; Czech, J; Czechtizky, W; Evers, A; Follmann, M; Kohlmann, M; Schiell, M; Kurz, M; Schreuder, HA; Kallus, C Novel Small Molecule Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (TAFIa) from Natural Product Anabaenopeptin. J Med Chem58:4839-44 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carboxypeptidase B |
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| Name: | Carboxypeptidase B |
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| Synonyms: | CBPB1_HUMAN | CPB | CPB1 | Carboxypeptidase B | PASP | PCPB | Pancreas-specific protein | Thrombin-activatable fibrinolysis (TAFI) |
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| Type: | Enzyme |
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| Mol. Mass.: | 47367.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P15086 |
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| Residue: | 417 |
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| Sequence: | MLALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQ
IKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATGHSYEKYN
KWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREW
ISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTH
TGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAY
LTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAG
GSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLEHLY
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| BDBM50089691 |
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| n/a |
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| Name | BDBM50089691 |
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| Synonyms: | CHEMBL3577425 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H46N4O4 |
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| Mol. Mass. | 478.6678 |
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| SMILES | CC1(C)C2CCC1(C)CC2NC(=O)[C@@H](CC1CCCCC1)NC(=O)N[C@@H](CCCCN)C(O)=O |r,TLB:10:9:5.4:1| |
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| Structure | 
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