| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
|---|
| Ligand | BDBM50090959 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1499669 (CHEMBL3584846) |
|---|
| Ki | 1047±n/a nM |
|---|
| Citation |  Slavik, R; Grether, U; Müller Herde, A; Gobbi, L; Fingerle, J; Ullmer, C; Krämer, SD; Schibli, R; Mu, L; Ametamey, SM Discovery of a high affinity and selective pyridine analog as a potential positron emission tomography imaging agent for cannabinoid type 2 receptor. J Med Chem58:4266-77 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cannabinoid receptor 2 |
|---|
| Name: | Cannabinoid receptor 2 |
|---|
| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CNR2_MOUSE | Cannabinoid CB2 receptor | Cannabinoid receptor | Cannabinoid receptor 2 | Cnr2 | mCB2 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 38220.43 |
|---|
| Organism: | MOUSE |
|---|
| Description: | P47936 |
|---|
| Residue: | 347 |
|---|
| Sequence: | MEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILS
SRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTAS
VGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCS
ELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLD
VRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYA
LRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT
|
|
|
|---|
| BDBM50090959 |
|---|
| n/a |
|---|
| Name | BDBM50090959 |
|---|
| Synonyms: | CHEMBL3582021 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H26F3N5O3 |
|---|
| Mol. Mass. | 501.5008 |
|---|
| SMILES | CC(C)(Cc1nnc(o1)-c1ccc(F)cc1)NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 |
|---|
| Structure | 
|
|---|
Search and Browse
