Reaction Details |
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Target | Programmed cell death 1 ligand 1 |
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Ligand | BDBM50091333 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1497759 (CHEMBL3583018) |
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IC50 | 110±n/a nM |
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Citation | Abdel-Magid, AF Inhibitors of the PD-1/PD-L1 Pathway Can Mobilize the Immune System: An Innovative Potential Therapy for Cancer and Chronic Infections. ACS Med Chem Lett6:489-90 (2015) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Programmed cell death 1 ligand 1 |
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Name: | Programmed cell death 1 ligand 1 |
Synonyms: | B7 homolog 1 | B7-H1 | B7H1 | B7H1 | CD274 | CD_antigen=CD274 | PD-L1 | PD1L1_HUMAN | PDCD1 ligand 1 | PDCD1L1 | PDCD1LG1 | PDL1 | Programmed cell death 1 ligand 1 | Programmed death ligand 1 |
Type: | PROTEIN |
Mol. Mass.: | 33278.49 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_109807 |
Residue: | 290 |
Sequence: | MRIFAVFIFMTYWHLLNAFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEME
DKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGG
ADYKRITVKVNAPYNKINQRILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGKTT
TTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNERTH
LVILGAILLCLGVALTFIFRLRKGRMMDVKKCGIQDTNSKKQSDTHLEET
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BDBM50091333 |
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n/a |
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Name | BDBM50091333 |
Synonyms: | CHEMBL3582253 |
Type | Small organic molecule |
Emp. Form. | C30H36N2O3 |
Mol. Mass. | 472.6184 |
SMILES | Cc1cc(CN2CCC(CC2)C(=O)NCCO)ccc1OCc1cccc(c1C)-c1ccccc1 |
Structure |
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