| Reaction Details |
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 | Report a problem with these data |
| Target | Atypical chemokine receptor 3 |
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| Ligand | BDBM50092260 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1499908 (CHEMBL3583502) |
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| IC50 | 1700±n/a nM |
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| Citation |  Oishi, S; Kuroyanagi, T; Kubo, T; Montpas, N; Yoshikawa, Y; Misu, R; Kobayashi, Y; Ohno, H; Heveker, N; Furuya, T; Fujii, N Development of novel CXC chemokine receptor 7 (CXCR7) ligands: selectivity switch from CXCR4 antagonists with a cyclic pentapeptide scaffold. J Med Chem58:5218-25 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Atypical chemokine receptor 3 |
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| Name: | Atypical chemokine receptor 3 |
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| Synonyms: | ACKR3 | ACKR3_HUMAN | C-X-C chemokine receptor type 7 | C-X-C chemokine receptor type 7 (CXCR7) | CMKOR1 | CXC-R7 | CXCR-7 | CXCR7 | Chemokine orphan receptor 1 | G-protein coupled receptor 159 | G-protein coupled receptor RDC1 homolog | GPR159 | RDC-1 | RDC1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 41498.84 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P25106 |
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| Residue: | 362 |
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| Sequence: | MDLHLFDYSEPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMI
ANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVT
HLIFSINLFGSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDT
YYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAIS
ASSDQEKHSSRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVT
QCLSLVHCCVNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQS
TK
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| BDBM50092260 |
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| n/a |
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| Name | BDBM50092260 |
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| Synonyms: | CHEMBL3581286 |
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| Type | Small organic molecule |
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| Emp. Form. | C40H60N12O7 |
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| Mol. Mass. | 820.9806 |
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| SMILES | [H][C@]12CCCN1C(=O)[C@H](Cc1ccc3ccccc3c1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@]([H])(NC(=O)[C@@]([H])(NC2=O)[C@@H](C)O)[C@@H](C)CC |r| |
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| Structure | 
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