| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] A |
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| Ligand | BDBM50093709 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1501477 (CHEMBL3586839) |
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| IC50 | 51.0±n/a nM |
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| Citation |  Khattab, SN; Haiba, NS; Asal, AM; Bekhit, AA; Amer, A; Abdel-Rahman, HM; El-Faham, A Synthesis and evaluation of quinazoline amino acid derivatives as mono amine oxidase (MAO) inhibitors. Bioorg Med Chem23:3574-85 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Amine oxidase [flavin-containing] A |
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| Name: | Amine oxidase [flavin-containing] A |
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| Synonyms: | AOFA_BOVIN | Amine oxidase [flavin-containing] A | MAO-A | MAOA | Monoamine Oxidase Type A (MAO-A) | Monoamine oxidase | Monoamine oxidase A | Monoamine oxidase type A |
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| Type: | PROTEIN |
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| Mol. Mass.: | 59764.63 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_1501477 |
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| Residue: | 527 |
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| Sequence: | MESLQKTSDAGQMFDVVVIGGGISGLSAAKLLAEHEVNVLVLEARERVGGRTYTVRNEHV
DYVDVGGAYVGPTQNRILRLSKQLGLETYKVNVNERLVHYVKGKTYPFRGAFPPVWNPIA
YLDYNNLWRTMDNMGKEIPADAPWEAPHAVEWDKMTMKDLIEKICWTKTARQFASLFVNI
NVTSEPHEVSALWFLWYVKQCGGTTRIFSITNGGQERKFVGGSGQVSERIMQLLGDRVKL
RSPVTYVDQSSENITVETLNRELYECRYVISAIPPTLTAKIHFRPELPSERNQLIQRLPM
GAVIKCMMYYKEAFWKKKDYCGCMIIEDEEAPISITLDDTKPDGSLPAIMGFILARKADR
LAKVHKDIRKRKICELYAKVLGSQEALHPVHYEEKNWCQEQYSGGCYTAYFPPGIMTQYG
RVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALGKLSAKDIWIQEPEAED
VPAVEITPSFWERNLPSVSGLLKIVGFSTSITALWFVMYRFRLLSRS
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| BDBM50093709 |
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| n/a |
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| Name | BDBM50093709 |
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| Synonyms: | CHEMBL3585840 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H17ClN4O2 |
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| Mol. Mass. | 344.795 |
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| SMILES | NNC(=O)CCN1C(Nc2ccccc2C1=O)c1ccc(Cl)cc1 |
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| Structure | 
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