| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
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| Ligand | BDBM50097466 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1501478 (CHEMBL3586840) |
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| IC50 | 440000±n/a nM |
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| Citation |  Khattab, SN; Haiba, NS; Asal, AM; Bekhit, AA; Amer, A; Abdel-Rahman, HM; El-Faham, A Synthesis and evaluation of quinazoline amino acid derivatives as mono amine oxidase (MAO) inhibitors. Bioorg Med Chem23:3574-85 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Amine oxidase [flavin-containing] B |
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| Name: | Amine oxidase [flavin-containing] B |
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| Synonyms: | AOFB_BOVIN | Amine oxidase [flavin-containing] B | MAO-B | MAOB | Monoamine Oxidase Type B (MAO-B) | Monoamine oxidase | Monoamine oxidase B | Monoamine oxidase type B |
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| Type: | PROTEIN |
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| Mol. Mass.: | 58428.94 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_1501478 |
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| Residue: | 520 |
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| Sequence: | MSSKCDVVVVGGGISGMAAAKLLHDSGLNVIVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNHILRLSKELGLETYKVNEVERLIHHTKGKSYPFRGSFPSVWNPITYLDHNNLWR
TMDDMGREIPSDAPWKAPLAEQWDLMTMKELLDKICWTESSKQLAILFVNLCVTAEIHEV
SALWFLWYVKQCGGTTRIFSTSNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIHIDQ
TGENVLVETLNHELYEAKYVISAVPPVLGMKIHFNPPLPMMRNQLITRVPLGSVIKSIVY
YKEPFWRNMDYCGSMIIEGEEAPVAYALDDTKPDGSYPAIIGFILAHKARKLARLTKEER
LKKLCDLYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTSYFPPGIMTQYGRVLRQPVGR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWLPEPESVDVPAKPITTT
FLQRHLPSVPGLLKLIGLTTIFSATALGFLAHKRGLLVRI
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| BDBM50097466 |
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| n/a |
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| Name | BDBM50097466 |
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| Synonyms: | CHEMBL3585810 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H20N2O3 |
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| Mol. Mass. | 264.3202 |
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| SMILES | COC(=O)CCCCCNC(=O)c1ccccc1N |
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| Structure | 
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