Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetN-formyl peptide receptor 2
LigandBDBM50097566
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1504343
EC50 230±n/a nM
Citation Lacivita ESchepetkin IAStama MLKirpotina LNColabufo NAPerrone RKhlebnikov AIQuinn MTLeopoldo M Novel 3-(1H-indol-3-yl)-2-[3-(4-methoxyphenyl)ureido]propanamides as selective agonists of human formyl-peptide receptor 2. Bioorg Med Chem 23:3913-24 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
N-formyl peptide receptor 2
Name:N-formyl peptide receptor 2
Synonyms:ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:38968.35
Organism:Homo sapiens (Human)
Description:P25090
Residue:351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVT
TICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIA
LDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNF
ASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPL
RVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPM
LYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50097566
n/a
NameBDBM50097566
Synonyms:CHEMBL3589946
TypeSmall organic molecule
Emp. Form.C32H37N5O4
Mol. Mass.555.6673
SMILESCOc1ccc(NC(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)NCC2(CCCCC2)c2ccc(OC)cn2)cc1 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: