| Reaction Details |
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 | Report a problem with these data |
| Target | Ghrelin O-acyltransferase |
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| Ligand | BDBM50094875 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1502747 (CHEMBL3590857) |
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| IC50 | >1000±n/a nM |
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| Citation |  Zhao, F; Darling, JE; Gibbs, RA; Hougland, JL A new class of ghrelin O-acyltransferase inhibitors incorporating triazole-linked lipid mimetic groups. Bioorg Med Chem Lett25:2800-3 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Ghrelin O-acyltransferase |
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| Name: | Ghrelin O-acyltransferase |
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| Synonyms: | GOAT | Ghrelin O-acyltransferase (GOAT) | MBOA4_HUMAN | MBOAT4 | Membrane-bound O-acyltransferase domain-containing protein 4 | O-acyltransferase domain-containing protein 4 | OACT4 |
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| Type: | Enzyme |
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| Mol. Mass.: | 49733.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q96T53 |
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| Residue: | 435 |
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| Sequence: | MEWLWLFFLHPISFYQGAAFPFALLFNYLCIMDSFSTRARYLFLLTGGGALAVAAMGSYA
VLVFTPAVCAVALLCSLAPQQVHRWTFCFQMSWQTLCHLGLHYTEYYLHEPPSVRFCITL
SSLMLLTQRVTSLSLDICEGKVKAASGGFRSRSSLSEHVCKALPYFSYLLFFPALLGGSL
CSFQRFQARVQGSSALHPRHSFWALSWRGLQILGLECLNVAVSRVVDAGAGLTDCQQFEC
IYVVWTTAGLFKLTYYSHWILDDSLLHAAGFGPELGQSPGEEGYVPDADIWTLERTHRIS
VFSRKWNQSTARWLRRLVFQHSRAWPLLQTFAFSAWWHGLHPGQVFGFVCWAVMVEADYL
IHSFANEFIRSWPMRLFYRTLTWAHTQLIIAYIMLAVEVRSLSSLWLLCNSYNSVFPMVY
CILLLLLAKRKHKCN
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| BDBM50094875 |
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| n/a |
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| Name | BDBM50094875 |
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| Synonyms: | CHEMBL3589130 |
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| Type | Small organic molecule |
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| Emp. Form. | C35H49N9O6 |
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| Mol. Mass. | 691.8203 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cn1cc(CCCCc2ccccc2)nn1)NC(=O)[C@H](CO)NC(=O)CN)C(N)=O |r| |
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| Structure | 
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