| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 2 |
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| Ligand | BDBM45816 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1505686 (CHEMBL3594606) |
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| Ki | >50000±n/a nM |
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| Citation |  Cvijetic, IN; Tanç, M; Juranic, IO; Verbic, T?; Supuran, CT; Drakulic, BJ 5-Aryl-1H-pyrazole-3-carboxylic acids as selective inhibitors of human carbonic anhydrases IX and XII. Bioorg Med Chem23:4649-59 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 2 |
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| Name: | Carbonic anhydrase 2 |
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| Synonyms: | CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29250.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00918 |
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| Residue: | 260 |
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| Sequence: | MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
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| BDBM45816 |
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| n/a |
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| Name | BDBM45816 |
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| Synonyms: | 3-(4-propan-2-ylphenyl)-1H-pyrazole-5-carboxylic acid | 3-p-cumenyl-1H-pyrazole-5-carboxylic acid | MLS-0091970.0001 | cid_975396 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H14N2O2 |
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| Mol. Mass. | 230.2625 |
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| SMILES | CC(C)c1ccc(cc1)-c1cc([nH]n1)C(O)=O |
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| Structure | 
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