| Reaction Details |
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 | Report a problem with these data |
| Target | Beta sliding clamp |
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| Ligand | BDBM50096638 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1495912 (CHEMBL3579723) |
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| IC50 | 134000±n/a nM |
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| Citation |  Yin, Z; Whittell, LR; Wang, Y; Jergic, S; Ma, C; Lewis, PJ; Dixon, NE; Beck, JL; Kelso, MJ; Oakley, AJ Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs. J Med Chem58:4693-702 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta sliding clamp |
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| Name: | Beta sliding clamp |
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| Synonyms: | Beta clamp | Beta sliding clamp | DNA polymerase III subunit beta | DPO3B_ECOLI | JW3678 | dnaN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40578.60 |
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| Organism: | Escherichia coli (strain K12) |
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| Description: | ChEMBL_109765 |
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| Residue: | 366 |
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| Sequence: | MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV
QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD
DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC
SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR
FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE
EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV
VMPMRL
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| BDBM50096638 |
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| n/a |
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| Name | BDBM50096638 |
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| Synonyms: | CHEMBL3577268 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H12ClNO2 |
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| Mol. Mass. | 249.693 |
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| SMILES | OC(=O)[C@@H]1CCc2c(C1)[nH]c1ccc(Cl)cc21 |r| |
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| Structure | 
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