Reaction Details | |||
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Target | Mu-type opioid receptor | ||
Ligand | BDBM50100987 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_1452451 (CHEMBL3362475) | ||
Ki | 12±n/a nM | ||
Citation | Schunk, S; Linz, K; Frormann, S; Hinze, C; Oberbörsch, S; Sundermann, B; Zemolka, S; Englberger, W; Germann, T; Christoph, T; Kögel, BY; Schröder, W; Harlfinger, S; Saunders, D; Kless, A; Schick, H; Sonnenschein, H Discovery of Spiro[cyclohexane-dihydropyrano[3,4-b]indole]-amines as Potent NOP and Opioid Receptor Agonists. ACS Med Chem Lett5:851-6 (2014) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Mu-type opioid receptor | |||
Name: | Mu-type opioid receptor | ||
Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 44789.51 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P35372 | ||
Residue: | 400 | ||
Sequence: |
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BDBM50100987 | |||
n/a | |||
Name | BDBM50100987 | ||
Synonyms: | CHEMBL3325748 | ||
Type | Small organic molecule | ||
Emp. Form. | C21H28ClNO | ||
Mol. Mass. | 345.906 | ||
SMILES | Cl.CN(C)[C@]1(CC[C@@H](CC1)OCc1ccccc1)c1ccccc1 |r,wU:4.2,wD:7.9,(41.68,-9.46,;38.57,-8.8,;37.23,-8.03,;37.23,-6.49,;35.9,-8.81,;35.13,-10.14,;33.59,-10.14,;32.82,-8.82,;33.58,-7.48,;35.12,-7.48,;31.27,-8.79,;30.49,-10.11,;28.95,-10.09,;28.2,-8.74,;26.66,-8.72,;25.87,-10.05,;26.63,-11.4,;28.17,-11.41,;36.69,-10.13,;35.95,-11.47,;36.74,-12.79,;38.29,-12.76,;39.03,-11.4,;38.23,-10.09,)| | ||
Structure |