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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Mu-type opioid receptor | ||
| Ligand | BDBM50101101 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1453325 (CHEMBL3366609) | ||
| Ki | 2.7±n/a nM | ||
| Citation |  Schunk, S; Linz, K; Hinze, C; Frormann, S; Oberbörsch, S; Sundermann, B; Zemolka, S; Englberger, W; Germann, T; Christoph, T; Kögel, BY; Schröder, W; Harlfinger, S; Saunders, D; Kless, A; Schick, H; Sonnenschein, H Discovery of a Potent Analgesic NOP and Opioid Receptor Agonist: Cebranopadol. ACS Med Chem Lett5:857-62 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Mu-type opioid receptor | |||
| Name: | Mu-type opioid receptor | ||
| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 44789.51 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P35372 | ||
| Residue: | 400 | ||
| Sequence: |
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| BDBM50101101 | |||
| n/a | |||
| Name | BDBM50101101 | ||
| Synonyms: | CHEMBL3325960 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C31H38N2O8 | ||
| Mol. Mass. | 566.642 | ||
| SMILES | OC(=O)CC(O)(CC(O)=O)C(O)=O.CN(C)[C@]1(CC[C@@]2(CC1)OCCc1c2[nH]c2ccc(C)cc12)c1ccccc1 |r,wU:16.14,wD:19.21,(14.07,-29.66,;15.4,-30.42,;16.72,-29.66,;15.4,-31.95,;14.07,-32.71,;12.75,-31.95,;14.83,-34.03,;16.36,-34.04,;17.12,-35.36,;17.12,-32.72,;13.31,-34.03,;14.07,-35.35,;11.78,-34.02,;3.79,-34.96,;4.89,-36.05,;6.38,-35.64,;4.5,-37.55,;3.72,-38.88,;2.19,-38.87,;1.43,-37.54,;2.19,-36.21,;3.73,-36.22,;.52,-38.8,;-1.03,-38.64,;-1.67,-37.22,;-.75,-35.97,;.8,-36.13,;1.43,-34.72,;.28,-33.68,;.27,-32.13,;-1.07,-31.36,;-2.41,-32.14,;-3.74,-31.36,;-2.4,-33.68,;-1.07,-34.45,;6.03,-37.56,;6.8,-38.9,;8.34,-38.91,;9.12,-37.58,;8.34,-36.23,;6.8,-36.23,)| | ||
| Structure | 
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