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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Mu-type opioid receptor | ||
| Ligand | BDBM50101099 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1453325 (CHEMBL3366609) | ||
| Ki | 0.390000±n/a nM | ||
| Citation |  Schunk, S; Linz, K; Hinze, C; Frormann, S; Oberbörsch, S; Sundermann, B; Zemolka, S; Englberger, W; Germann, T; Christoph, T; Kögel, BY; Schröder, W; Harlfinger, S; Saunders, D; Kless, A; Schick, H; Sonnenschein, H Discovery of a Potent Analgesic NOP and Opioid Receptor Agonist: Cebranopadol. ACS Med Chem Lett5:857-62 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Mu-type opioid receptor | |||
| Name: | Mu-type opioid receptor | ||
| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 44789.51 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P35372 | ||
| Residue: | 400 | ||
| Sequence: |
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| BDBM50101099 | |||
| n/a | |||
| Name | BDBM50101099 | ||
| Synonyms: | CHEMBL3326228 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H30ClN3 | ||
| Mol. Mass. | 395.968 | ||
| SMILES | Cl.CN(C)[C@]1(CC[C@@]2(CC1)NCCc1c2[nH]c2ccccc12)c1ccccc1 |r,wU:4.2,wD:7.9,(19.24,-9.37,;10.32,-12.36,;8.84,-12.77,;7.74,-11.68,;8.44,-14.27,;7.67,-15.59,;6.14,-15.59,;5.38,-14.26,;6.14,-12.93,;7.68,-12.94,;4.47,-15.52,;2.93,-15.35,;2.3,-13.94,;3.21,-12.69,;4.75,-12.85,;5.38,-11.44,;4.23,-10.41,;4.23,-8.85,;2.89,-8.09,;1.56,-8.86,;1.56,-10.41,;2.89,-11.18,;9.98,-14.28,;10.74,-15.62,;12.28,-15.63,;13.06,-14.29,;12.29,-12.95,;10.75,-12.95,)| | ||
| Structure | 
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