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TargetMu-type opioid receptor
LigandBDBM50325534
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1432427
Ki 0.430000±n/a nM
Citation Watanabe YKitazawa SFujii HNemoto THirayama SIwai TGouda HHirono SNagasea H Design, synthesis, and structure-activity relationship of novel opioid┐ receptor selective agonists:a-iminoamide derivatives with an azabicyclo[2.2.2]octene skeleton. Bioorg Med Chem Lett 24:4980-3 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Mu-type opioid receptor
Synonyms:M-OR-1 | MOR-1 | Mor | OPIATE Mu | Oprm | Oprm1
Type:Enzyme Catalytic Domain
Mol. Mass.:44431.62
Organism:MOUSE
Description:OPIATE Mu OPRM1 MOUSE::P42866
Residue:398
Sequence:
MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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  Blast E-value cutoff:
BDBM50325534
n/a
NameBDBM50325534
Synonyms:CHEMBL267495 | nalfurafine
TypeSmall organic molecule
Emp. Form.C28H32N2O5
Mol. Mass.476.5641
SMILESCN([C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45)C(=O)\C=C\c1ccoc1
Structure
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