| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 22 member 8 |
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| Ligand | BDBM50103524 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1482571 (CHEMBL3537392) |
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| IC50 | 35700±n/a nM |
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| Citation |  Wolman, AT; Gionfriddo, MR; Heindel, GA; Mukhija, P; Witkowski, S; Bommareddy, A; Vanwert, AL Organic anion transporter 3 interacts selectively with lipophilicß-lactam antibiotics. Drug Metab Dispos41:791-800 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 22 member 8 |
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| Name: | Solute carrier family 22 member 8 |
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| Synonyms: | Oat3 | Oat3 | Organic anion transporter 3 | Reduced in osteosclerosis transporter | Roct | S22A8_MOUSE | Slc22a8 | Solute carrier family 22 member 8 | mOat3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 59254.18 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_104613 |
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| Residue: | 537 |
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| Sequence: | MTFSEILDRVGSMGPFQYLHVTLLALPILGIANHNLLQIFTATTPDHHCRPPPNASLEPW
VLPLGPNGKPEKCLRFVHLPNASLPNDTQGATEPCLDGWIYNSTRDTIVTEWDLVCGSNK
LKEMAQSVFMAGILVGGPVFGELSDRFGRKPILTWSYLLLAASGSSAAFSPSLTVYMIFR
FLCGCSISGISLSTIILNVEWVPTSTRAISSTTIGYCYTIGQFILPGLAYAVPQWRWLQL
SVSAAFFIFSLLSWWVPESIRWLVLSGKFSKALKTLQRVATFNGKKEEGEKLTVEELKFN
LQKDITSAKVKYGLSDLFRVSILRRVTFCLSLAWFATGFAYYSLAMGVEEFGVNIYILQI
IFGGVDIPAKFITILSISYLGRRITQGFLLILAGVAILALIFVSSEMQLLRTALAVFGKG
CLSGSFSCLFLYTSELYPTVLRQTGMGISNIWARVGSMIAPLVKITGELQPFIPNVIFGT
MTLLGGSAAFFLLETLNRPLPETIEDIQDWYQQTKKTKQEPEAEKASQTIPLKTGGP
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| BDBM50103524 |
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| n/a |
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| Name | BDBM50103524 |
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| Synonyms: | Ceftiofur |
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| Type | Small organic molecule |
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| Emp. Form. | C19H17N5O7S3 |
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| Mol. Mass. | 523.563 |
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| SMILES | [H][C@]12SCC(CSC(=O)c3ccco3)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1csc(N)n1)C(O)=O |c:14| |
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| Structure | 
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