| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 22 member 8 |
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| Ligand | BDBM50350467 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1482579 (CHEMBL3537400) |
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| Ki | 8620±n/a nM |
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| Citation |  Wolman, AT; Gionfriddo, MR; Heindel, GA; Mukhija, P; Witkowski, S; Bommareddy, A; Vanwert, AL Organic anion transporter 3 interacts selectively with lipophilicß-lactam antibiotics. Drug Metab Dispos41:791-800 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 22 member 8 |
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| Name: | Solute carrier family 22 member 8 |
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| Synonyms: | OAT3 | Organic anion transporter 3 | S22A8_HUMAN | SLC22A8 | hOAT3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 59870.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1486920 |
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| Residue: | 542 |
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| Sequence: | MTFSEILDRVGSMGHFQFLHVAILGLPILNMANHNLLQIFTAATPVHHCRPPHNASTGPW
VLPMGPNGKPERCLRFVHPPNASLPNDTQRAMEPCLDGWVYNSTKDSIVTEWDLVCNSNK
LKEMAQSIFMAGILIGGLVLGDLSDRFGRRPILTCSYLLLAASGSGAAFSPTFPIYMVFR
FLCGFGISGITLSTVILNVEWVPTRMRAIMSTALGYCYTFGQFILPGLAYAIPQWRWLQL
TVSIPFFVFFLSSWWTPESIRWLVLSGKSSKALKILRRVAVFNGKKEEGERLSLEELKLN
LQKEISLAKAKYTASDLFRIPMLRRMTFCLSLAWFATGFAYYSLAMGVEEFGVNLYILQI
IFGGVDVPAKFITILSLSYLGRHTTQAAALLLAGGAILALTFVPLDLQTVRTVLAVFGKG
CLSSSFSCLFLYTSELYPTVIRQTGMGVSNLWTRVGSMVSPLVKITGEVQPFIPNIIYGI
TALLGGSAALFLPETLNQPLPETIEDLENWSLRAKKPKQEPEVEKASQRIPLQPHGPGLG
SS
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| BDBM50350467 |
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| n/a |
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| Name | BDBM50350467 |
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| Synonyms: | BL-S578 | CEFADROXIL | Cefadrops |
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| Type | Small organic molecule |
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| Emp. Form. | C16H17N3O5S |
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| Mol. Mass. | 363.388 |
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| SMILES | CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c1ccc(O)cc1)C2=O)C(O)=O |r,t:1| |
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| Structure | 
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