| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 1A2 |
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| Ligand | BDBM50062614 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1493769 (CHEMBL3530852) |
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| IC50 | >30000±n/a nM |
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| Citation |  Lee, CA; Jones, JP; Katayama, J; Kaspera, R; Jiang, Y; Freiwald, S; Smith, E; Walker, GS; Totah, RA Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity. Drug Metab Dispos40:943-51 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 1A2 |
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| Name: | Cytochrome P450 1A2 |
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| Synonyms: | CP1A2_HUMAN | CYP1A2 | CYPIA2 | Cholesterol 25-hydroxylase | Cytochrome P(3)450 | Cytochrome P450 1A | Cytochrome P450 1A2 (CYP1A2) | Cytochrome P450 4 | Cytochrome P450-P3 |
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| Type: | Enzyme |
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| Mol. Mass.: | 58423.38 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P05177 |
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| Residue: | 516 |
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| Sequence: | MALSQSVPFSATELLLASAIFCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGKN
PHLALSRMSQRYGDVLQIRIGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDG
QSLTFSTDSGPVWAARRRLAQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQELM
AGPGHFDPYNQVVVSVANVIGAMCFGQHFPESSDEMLSLVKNTHEFVETASSGNPLDFFP
ILRYLPNPALQRFKAFNQRFLWFLQKTVQEHYQDFDKNSVRDITGALFKHSKKGPRASGN
LIPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLS
DRPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPEL
WEDPSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLE
FSVPPGVKVDLTPIYGLTMKHARCEHVQARLRFSIN
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| BDBM50062614 |
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| n/a |
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| Name | BDBM50062614 |
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| Synonyms: | CHEMBL900 | Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine | Disipal | Invagesic | N,N-dimethyl-2-(phenyl(o-tolyl)methoxy)ethanamine | Norflex | Norgesic | ORPHENADRINE | Orphengesic |
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| Type | Small organic molecule |
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| Emp. Form. | C18H23NO |
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| Mol. Mass. | 269.3813 |
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| SMILES | CN(C)CCOC(c1ccccc1)c1ccccc1C |
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| Structure | 
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