Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | Cytochrome P450 2J2 | ||
Ligand | BDBM54795 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_1485701 (CHEMBL3541093) | ||
IC50 | >50000±n/a nM | ||
Citation | Ren, S; Zeng, J; Mei, Y; Zhang, JZ; Yan, SF; Fei, J; Chen, L Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug Metab Dispos41:60-71 (2012) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Cytochrome P450 2J2 | |||
Name: | Cytochrome P450 2J2 | ||
Synonyms: | CP2J2_HUMAN | CYP2J2 | ||
Type: | Enzyme | ||
Mol. Mass.: | 57623.04 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P51589 | ||
Residue: | 502 | ||
Sequence: |
| ||
BDBM54795 | |||
n/a | |||
Name | BDBM54795 | ||
Synonyms: | (4R,4aS,7aR,12bS)-3-allyl-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride | (4R,4aS,7aR,12bS)-4a,9-bis(oxidanyl)-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride | (4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride | MLS000069540 | NALOXONE HYDROCHLORIDE | SMR000058766 | cid_5464092 | ||
Type | Small organic molecule | ||
Emp. Form. | C19H21NO4 | ||
Mol. Mass. | 327.3743 | ||
SMILES | Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O | ||
Structure |