| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily E member 1 |
|---|
| Ligand | BDBM50103543 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1434849 (CHEMBL3384646) |
|---|
| IC50 | 27000±n/a nM |
|---|
| Citation |  Scott, JS; Bowker, SS; Brocklehurst, KJ; Brown, HS; Clarke, DS; Easter, A; Ertan, A; Goldberg, K; Hudson, JA; Kavanagh, S; Laber, D; Leach, AG; MacFaul, PA; Martin, EA; McKerrecher, D; Schofield, P; Svensson, PH; Teague, J Circumventing seizure activity in a series of G protein coupled receptor 119 (GPR119) agonists. J Med Chem57:8984-98 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Potassium voltage-gated channel subfamily E member 1 |
|---|
| Name: | Potassium voltage-gated channel subfamily E member 1 |
|---|
| Synonyms: | Delayed rectifier potassium channel subunit IsK | IKs producing slow voltage-gated potassium channel subunit beta Mink | KCNE1 | KCNE1_HUMAN | KCNQ1(Kv7.1)/KCNE1(MinK) | Minimal potassium channel | Voltage-gated potassium channel beta subunit Mink | Voltage-gated potassium channel, IKs |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 14676.11 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1456351 |
|---|
| Residue: | 129 |
|---|
| Sequence: | MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLG
IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT
HLPETKPSP
|
|
|
|---|
| BDBM50103543 |
|---|
| n/a |
|---|
| Name | BDBM50103543 |
|---|
| Synonyms: | CHEMBL3358006 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H22F4N6O4S |
|---|
| Mol. Mass. | 530.496 |
|---|
| SMILES | C[C@@H]1CN(CCN1c1ncc(OCc2ccc(CS(C)(=O)=O)cc2F)cn1)c1nc(no1)C(F)(F)F |r| |
|---|
| Structure | 
|
|---|
Search and Browse
